Mednosis LogoMednosis
← All Research

Precision Medicine & AI

RSS

Research and developments at the intersection of artificial intelligence and healthcare.

Why it matters: AI is transforming how we diagnose, treat, and prevent disease. Staying informed helps clinicians and patients make better decisions.

Related:DiagnosticsClinical TrialRegulatory

4 research items

Get updates on this topic
Sort by DateSort by Relevance
Drug Watch
Fibroblast growth factor receptor inhibition for succinate dehydrogenase-deficient gastrointestinal stromal tumors: a phase 2 trial
From: 2026-05-28
Nature Medicine - AI Section⭐Promising2 min read

New drug targets rare, drug-resistant stomach tumors

Key Takeaway:

A new phase 2 trial shows that the drug rogaratinib successfully targets a genetic switch to treat rare, drug-resistant gastrointestinal tumors.

A clinical trial published in Nature Medicine evaluated a drug called rogaratinib for patients with a specific, hard-to-treat subtype of gastrointestinal stromal tumors. These tumors lack a key enzyme, making them resistant to standard cancer drugs. Rogaratinib works by blocking a different cellular pathway, bypassing the tumor's natural resistance. The trial demonstrated encouraging clinical success, proving that targeting this alternative genetic switch is an effective way to treat patients who previously had very few therapeutic options.

What this means for you

This early-stage study shows a new drug, rogaratinib, may help treat a rare type of stomach tumor. It is not yet widely available, and patients should not change their current treatments.

OncologyClinical TrialGastroenterologyPrecision Medicine

Citation:

Nature Medicine - AI Section, 2026. DOI: s41591-026-04376-9 Read article →

Guideline Update
Five tenets for advancing evidence-based precision medicine
From: 2026-03-23
Nature Medicine - AI Section⭐Exploratory3 min read

Five core principles proposed to standardize and advance precision medicine

Key Takeaway:

Researchers identify five principles to improve precision medicine, aiming for treatments that are effective, reproducible, widely applicable, and fair to all patients.

Researchers analyzed current precision medicine practices and identified key challenges that prevent individual-specific treatments from being widely adopted. To address this, they established five foundational principles aimed at making precision medicine more clinically meaningful, reproducible, scalable, and equitable. By incorporating insights from clinical trials and genomics, these guidelines provide a structured framework to help healthcare systems integrate personalized treatments into routine clinical practice safely and effectively.

What this means for you

"Exciting research in precision medicine, but it's still early. It may take years before it's available in clinics. Continue with your current care plan and discuss any questions with your doctor."

Precision MedicineClinical DecisionObservational Study

Citation:

Nature Medicine - AI Section, 2026. DOI: s41591-026-04309-6 Read article →

Guideline Update
Five tenets for advancing evidence-based precision medicine
From: 2026-03-20
Nature Medicine - AI Section⭐Exploratory3 min read

Scientists propose five rules to make precision medicine fair and reliable

Key Takeaway:

Researchers propose a new framework to improve precision medicine, aiming for more reliable and fair health outcomes in the coming years.

A new study published in Nature Medicine introduces five core tenets designed to guide the future of evidence-based precision medicine. Using a mix of qualitative reviews of current medical models and quantitative data on patient outcomes, the researchers identified major gaps in how personalized treatments are currently delivered. Their proposed framework outlines steps to make precision medicine more reproducible, scalable, and equitable, ensuring that cutting-edge, gene-tailored therapies actually deliver consistent clinical results and do not leave underserved patient populations behind.

What this means for you

This research is promising for future personalized treatments, but it's still early. It may take years before it's available. Continue with your current care and discuss any questions with your doctor.

Precision MedicineClinical DecisionSystematic ReviewOncology

Citation:

Nature Medicine - AI Section, 2026. DOI: s41591-026-04309-6 Read article →

From: 2025-12-15
ArXiv - Quantitative BiologyExploratory3 min read

Next-gen blood analyzers bring personalized medicine to hematology

Key Takeaway:

Next-Generation Hematology Analyzers offer more precise blood diagnostics and personalized treatment options, improving care for blood disorders, with advancements expected to be widely available soon.

Researchers have evaluated Next-Generation Hematology Analyzers that use advanced machine learning to study blood cells in unprecedented detail. Unlike traditional machines that only provide basic cell counts, these new analyzers evaluate cell shape and function. This deeper look helps doctors diagnose blood disorders much earlier and tailor therapies to the individual patient, with the technology expected to be widely available soon.

What this means for you

Exciting research on new blood test technology, but it's not yet in clinics. It may take years to become available. Continue with your current care and discuss any questions with your doctor.

HematologyDiagnostic AIPrecision Medicine

Citation:

ArXiv, 2025. arXiv: 2512.12248 Read article →

Exploring Precision Medicine? Learn how to interpret medical AI research →